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Journal: Communications Biology
Article Title: The functional brain favours segregated modular connectivity at old age unless affected by neurodegeneration
doi: 10.1038/s42003-021-02497-0
Figure Lengend Snippet: a Resting-state functional MRI pre-processing pipeline and time-series extraction from functional atlases. b Pearson correlation matrices. c Optimal local threshold estimation; the network edge density at which Q−Q rand is maximum. d Thresholded matrices by optimal density using local and global threshold network construction methods. e Louvain’s community and modular dissociation (MD) estimation, see also Supplementary Fig . f Modular variability (MV) using consensus community. g Group means MD; subcortical regions and cerebellum showed in all groups high MD while motor-sensory, frontal, temporal pole and occipital cortex show low MD. h Group mean MV; patterns of high and low MV were consistent across all groups. Motor-sensory, occipital, and temporal pole showed low MV while parietal, ventral frontal and insulo-opercular cortices showed high MV.
Article Snippet: For this, the Hadamard product between the binarised matrix and the original weighted matrix was computed, and used for community structure and modularity statistic estimation using the
Techniques: Functional Assay, Extraction